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In Group B, after application of topical anesthetic, adequate passes using dermaroller were made which was followed by topical application of 1% copper peptide serum

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This active compound is likely to inhibit the activation of nuclear factor-κB (NF-κB) through the TLR4/MAPKs/NF-κB pathways, thus downregulating the expression of pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α